Microsoft Antimalware has encountered an error trying to update signatures. - Windows 7 Pro

We are seeing this on a Windows 7 PC connected to a Windows 2016 domain:

Log Name:      System
Source:        Microsoft Antimalware
Date:          17/09/2019 07:27:38
Event ID:      2001
Task Category: None
Level:         Error
Keywords:      Classic
User:          N/A
Computer:      pc.DOMAIN.local
Description:
Microsoft Antimalware has encountered an error trying to update signatures.
  New Signature Version:
  Previous Signature Version: 1.301.1414.0
  Update Source: Microsoft Update Server
  Update Stage: Download
  Source Path: http://www.microsoft.com
  Signature Type: AntiVirus
  Update Type: Full
  User: NT AUTHORITY\SYSTEM
  Current Engine Version:
  Previous Engine Version: 1.1.16300.1
  Error code: 0x8024001e
  Error description: An unexpected problem occurred while checking for updates. For information on installing or troubleshooting updates, see Help and Support.
Event Xml:
<Event xmlns="http://schemas.microsoft.com/win/2004/08/events/event">
  <System>
    <Provider Name="Microsoft Antimalware" />
    <EventID Qualifiers="0">2001</EventID>
    <Level>2</Level>
    <Task>0</Task>
    <Keywords>0x80000000000000</Keywords>
    <TimeCreated SystemTime="2019-09-17T06:27:38.000000000Z" />
    <EventRecordID>496414</EventRecordID>
    <Channel>System</Channel>
    <Computer>pc.DOMAIN.local</Computer>
    <Security />
  </System>
  <EventData>
    <Data>%%860</Data>
    <Data>4.10.209.0</Data>
    <Data>
    </Data>
    <Data>1.301.1414.0</Data>
    <Data>7</Data>
    <Data>%%859</Data>
    <Data>
    </Data>
    <Data>NT AUTHORITY</Data>
    <Data>SYSTEM</Data>
    <Data>S-1-5-18</Data>
    <Data>1</Data>
    <Data>%%800</Data>
    <Data>1</Data>
    <Data>%%803</Data>
    <Data>
    </Data>
    <Data>1.1.16300.1</Data>
    <Data>0x8024001e</Data>
    <Data>An unexpected problem occurred while checking for updates. For information on installing or troubleshooting updates, see Help and Support. </Data>
    <Data>2</Data>
    <Data>%%853</Data>
    <Data>http://www.microsoft.com</Data>
  </EventData>

Can you do a manual update?

Is it getting stuck on one particular update?

If so, stop the Windows Update service and rename the SoftwareDistribution\Downloads folder in C:\Windows and restart the service and try the update manually again.